CENTROSOME POLARIZATION IN T CELLS: A TASK FOR FORMINS

T-cell antigen receptor (TCR) engagement triggers the rapid reorientation of the centrosome, which is associated with the secretory machinery, towards the immunological synapse (IS) for polarized protein trafficking.Recent evidence indicates that upon TCR triggering the INF2 formin, together gotrax handlebar with the formins DIA1 and FMNL1, promote

The importance of the research is showing the environmental, cultural and social value of the Arab rural Mediterranean Residence as a regional heritage, where the concept of heritage brings aesthetic and functional values, and is characterized by persistence and continuity together, as it is an honest record of community culture, unity of its human